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Kansas City quarterback Patrick Mahomes threw for 360 yards and five touchdowns as the Chiefs raced to a convincing 44-15 victory over the Arizona Cardinals in the season opener on Sunday.

Joe Burrow committed five turnovers and Evan McPherson missed a key extra point in the fourth quarter and a field goal in overtime as the Bengals lost their first game since Super Bowl LVI.

Chargers WR Keenan Allen has been ruled out for the rest of Sunday’s game against the Raiders with a hamstring injury.

Washington veteran quarterback Carson Wentz won his first game with his new team on Sunday, guiding the Commanders to a 28-22 victory over the Jacksonville Jaguars in Landover, Maryland.

In his first game in almost two years, Saints WR Michael Thomas caught five passes for 57 yards and two TDs. “I still have a lot more,” he said.

Multiple quarterbacks made their debuts in new cities and a wild Bengals-Steelers game ended in OT. Here’s what to know from Week 1.

Patriots QB Mac Jones suffered a back injury in Sunday’s season-opening 20-7 loss to the Dolphins and required X-rays on it after the game. He was not made available to the media.

Chiefs safety Justin Reid filled in for the injured Harrison Butker at kicker against the Cardinals on Sunday, making a PAT in the first quarter.

Ravens left tackle Ja’Wuan James has suffered a season-ending Achilles tendon tear for the second year in a row. Sunday was James’ first game played in three years.